Blar i forfatter "Tilden, Terje"

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    • Circulating cytokine levels in the treatment of comorbid anxiety disorders 

      Johnson, Sverre Urnes; Hoffart, Asle; Tilden, Terje; Toft, Helge Prytz; Neupane, Sudan; Lien, Lars; Bramness, Jørgen Gustav (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-28)
      Psychotherapy research aims to investigate predictors and moderators of treatment outcome, but there are few consistent findings. This study aimed to investigate cytokines in patients undergoing treatment for anxiety disorders and whether the level of cytokines moderated the treatment outcome. Thirty-seven patients with comorbid and treatment-resistant anxiety disorders were investigated using ...

    • Cytokine concentrations are related to level of mental distress in inpatients not using anti-inflammatory drugs 

      Toft, Helge Prytz; Lien, Lars; Neupane, Sudan Prasad; Abebe, Dawit Shawel; Tilden, Terje; Wampold, Bruce E.; Bramness, Jørgen G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-02)
      <p><i>Objective - </i>Cross-sectional data show elevated levels of circulating cytokines in psychiatric patients. The literature is divided concerning anti-inflammatory drugs’ ability to relieve symptoms, questioning a causal link between inflammatory pathways and psychiatric conditions. We hypothesised that the development of circulating cytokine levels is related to mental distress, and that this ...

    • The effect of trauma and alcohol on the relationship between level of cytokines and depression among patients entering psychiatric treatment 

      Toft, Helge Prytz; Neupane, Sudan Prasad; Bramness, Jørgen Gustav; Tilden, Terje; Wampold, Bruce E.; Lien, Lars (Journal article; Peer reviewed, 2018-04-10)
      <b>Background</b><br> Depression is associated with immunological responses as reflected by altered levels of circulating cytokines. Alcohol use and trauma may modulate immune activity, and few studies have investigated these factors in depressed patients. We aimed to explore the association between circulating peripheral cytokine levels and degree of depressive symptoms, taking trauma and alcohol ...

    • Persistent level of mental distress in PTSD patients is not reflected in cytokine levels 1 year after the treatment 

      Toft, Helge; Bramness, Jørgen Gustav; Tilden, Terje; Bolstad, Ingeborg; Lien, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-27)
      <i>Objective</i>: Cross-sectional data show that post-traumatic stress disorder (PTSD) patients often have increased levels of circulating inflammatory markers. There is, however, still a paucity of longitudinal studies with long follow-up times on levels of cytokines in such patients. The current study assesses patients with and without PTSD diagnosis 1 year after discharge from inpatient ...

    • PTSD patients show increasing cytokine levels during treatment despite reduced psychological distress 

      Toft, Helge Prytz; Bramness, Jørgen Gustav; Lien, Lars; Abebe, Dawit Shawel; Wampold, Bruce E.; Tilden, Terje; Hestad, Knut; Neupane, Sudan Prasad (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-17)
      <p><i>Background</i>: A reciprocal relationship between activated innate immune system and changes in mood and behavior has been established. There is still a paucity of knowledge on how the immune system responds during psychiatric treatment. We aimed to explore circulating cytokines and assess psychiatric symptom severity scores during 12 weeks of inpatient psychiatric treatment.</p> <p><i>Methods</i>: ...